Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B.
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice.
Gut ahead of print
pmid : 23172891
Riteau N, Baron L, Villeret B, Guillou N, Savigny F, Ryffel B, Rassendren F, Le Bert M, Gombault A, Couillin I.
ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation.
Cell Death Dis 3:e403
pmid : 23059822
Vitry MA, De Trez C, Goriely S, Dumoutier L, Akira S, Ryffel B, Carlier Y, Letesson JJ, Muraille E.
Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice.
Infect. Immun. 80:4271-80
pmid : 23006848
Su D, Musaji A, Legrain S, Detalle L, van der Kaa J, Verbeek JS, Ryffel B, Coutelier JP.
Antibody-independent thrombocytopenia in lactate dehydrogenase-elevating virus-infected mice.
J. Virol. 86:12414-6
pmid : 22933286
Rigato C, Swinnen N, Buckinx R, Couillin I, Mangin JM, Rigo JM, Legendre P, Le Corronc H.
Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion.
J. Neurosci. 32:11559-73
pmid : 22915101
Sorgi CA, Rose S, Court N, Carlos D, Paula-Silva FW, Assis PA, Frantz FG, Ryffel B, Quesniaux V, Faccioli LH.
GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands.
PLoS ONE 7:e40523
pmid : 22808181
Xu W, Lan Q, Chen M, Chen H, Zhu N, Zhou X, Wang J, Fan H, Yan CS, Kuang JL, Warburton D, Togbe D, Ryffel B, Zheng SG, Shi W.
Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation.
PLoS ONE 7:e40314
pmid : 22792275
Lan Q, Zhou X, Fan H, Chen M, Wang J, Ryffel B, Brand D, Ramalingam R, Kiela PR, Horwitz DA, Liu Z, Zheng SG.
Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome.
J Mol Cell Biol 4:409-19
pmid : 22773728
Su W, Fan H, Chen M, Wang J, Brand D, He X, Quesniaux V, Ryffel B, Zhu L, Liang D, Zheng SG.
Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1.
J. Allergy Clin. Immunol. 130:444-52.e7
pmid : 22738679
Ivanov S, Fontaine J, Paget C, Macho Fernandez E, Van Maele L, Renneson J, Maillet I, Wolf NM, Rial A, Léger H, Ryffel B, Frisch B, Chabalgoity JA, Sirard JC, Benecke A, Faveeuw C, Trottein F.
Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide.
J. Infect. Dis. 206:723-34
pmid : 22723642
Chen M, Guo Z, Ju W, Ryffel B, He X, Zheng SG.
The development and function of follicular helper T cells in immune responses.
Cell. Mol. Immunol. 9:375-9
pmid : 22659733
Sudres M, Ciré S, Vasseur V, Brault L, Da Rocha S, Boisgérault F, Le Bec C, Gross DA, Blouin V, Ryffel B, Galy A.
MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV.
Mol. Ther. 20:1571-81
pmid : 22643865
Kong N, Lan Q, Chen M, Wang J, Shi W, Horwitz DA, Quesniaux V, Ryffel B, Liu Z, Brand D, Zou H, Zheng SG.
Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance.
Arthritis Rheum. 64:2548-58
pmid : 22605463
Jiang HR, Milovanović M, Allan D, Niedbala W, Besnard AG, Fukada SY, Alves-Filho JC, Togbe D, Goodyear CS, Linington C, Xu D, Lukic ML, Liew FY.
IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages.
Eur. J. Immunol. 42:1804-14
pmid : 22585447
Perche O, Laudier B, Menuet A, Odent S, Laumonnier F, Briault S.
FG syndrome: the FGS2 locus revisited.
Am. J. Med. Genet. A 158A:1489-92
pmid : 22528511
Secher T, Rodrigues Coelho F, Noulin N, Lino Dos Santos Franco A, Quesniaux V, Lignon J, Mitchell J, Moser R, Gomes E, Mirotti L, Tavares-de-Lima W, Ryffel B, Vargaftig BB, Russo M.
Enhancement of methacholine-evoked tracheal contraction induced by bacterial lipopolysaccharides depends on epithelium and tumor necrosis factor.
J Allergy (Cairo) 2012:494085
pmid : 22481960
Chapman R, Shephard E, Stutz H, Douglass N, Sambandamurthy V, Garcia I, Ryffel B, Jacobs W, Williamson AL.
Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells.
PLoS ONE 7:e32769
pmid : 22479338
Copin R, Vitry MA, Hanot Mambres D, Machelart A, De Trez C, Vanderwinden JM, Magez S, Akira S, Ryffel B, Carlier Y, Letesson JJ, Muraille E.
In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice.
PLoS Pathog. 8:e1002575
pmid : 22479178
Terme M, Ullrich E, Aymeric L, Meinhardt K, Coudert JD, Desbois M, Ghiringhelli F, Viaud S, Ryffel B, Yagita H, Chen L, Mécheri S, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, Degli-Esposti M, Chaput N, Zitvogel L.
Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells.
Cancer research 72:2757-2767
pmid : 22427351
Chalmin F, Mignot G, Bruchard M, Chevriaux A, Végran F, Hichami A, Ladoire S, Derangère V, Vincent J, Masson D, Robson SC, Eberl G, Pallandre JR, Borg C, Ryffel B, Apetoh L, Rébé C, Ghiringhelli F.
Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression.
Immunity 36:362-73
pmid : 22406269
Paget C, Ivanov S, Fontaine J, Renneson J, Blanc F, Pichavant M, Dumoutier L, Ryffel B, Renauld JC, Gosset P, Gosset P, Si-Tahar M, Faveeuw C, Trottein F.
Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection: POTENTIAL ROLE IN PROTECTION AGAINST LUNG EPITHELIAL DAMAGES.
J. Biol. Chem. 287:8816-29
pmid : 22294696
Fauconnier M, Palomo J, Bourigault ML, Meme S, Szeremeta F, Beloeil JC, Danneels A, Charron S, Rihet P, Ryffel B, Quesniaux VF.
IL-12Rβ2 is essential for the development of experimental cerebral malaria.
J. Immunol. 188:1905-14
pmid : 22238458
Besnard AG, Togbe D, Couillin I, Tan Z, Zheng SG, Erard F, Le Bert M, Quesniaux V, Ryffel B.
Inflammasome-IL-1-Th17 response in allergic lung inflammation.
J Mol Cell Biol 4:3-10
pmid : 22147847
Lan Q, Fan H, Quesniaux V, Ryffel B, Liu Z, Zheng SG.
Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases?
J Mol Cell Biol 4:22-8
pmid : 22107826
Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM.
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.
Arthritis Rheum. 64:474-84
pmid : 21952942