Université d'Orléans

Publications 2018

  1. Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, Laurenceau D, Ryffel B, Apetoh L, Kiziltunc A, Uslu H, Sultan Albez F, Akgun M, Togbe D* and Quesniaux VFJ*. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nature Communications 9:5226 (2018) doi: 10.1038/s41467-018-07425-1  IF: 12.35

  2. Feat-Vetel J., Larrigaldie V., Meyer-Dilhet G., Herzine A., Mougin C., Laugeray A., Gefflaut T., Richard O., Quesniaux V., Montécot-Dubourg C., Mortaud S. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice NeuroToxicology 2018 October doi: 10.1016/j.neuro.2018.10.001 – in press


  3. Michaudel C, Mackowiak Claire, Maillet I, Fauconnier L, Akdis C, Sokolowska M, Dreher A, Tan H-T.T., Quesniaux V.F., Ryffel B and Togbe D. Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by Interleukin-33 J Allergy Clin Immun 2018 Jan 10. pii: S0091-6749(18)30028-9. doi: 10.1016/j.jaci.2017.11.044. PMID:29331644 IF:12.48

  4. Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann LF, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B and Pichlmair A. Oxeiptosis – a ROS induced caspase-independent cell death pathway. Nat Immunol. 19:130-140 (2018) PMID: 29255269

  5. Couturier-Maillard A, Froux N, Piotet-Morin J, Michaudel C, Brault L, Le Bérichel J, Sénéchal A, Robinet P, Chenuet P, Jejou S, Dumoutier L, Renauld J-C, Iovanna J, Huber S, Quesniaux VFJ, Sokol H and Ryffel B. IL-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation. Mucosal Immunol (2018, in press)

  6. Marinho* F.V., Benmerzoug* S., Rose S., Priscila C. Campos, Báfica A., Marques J, Barber G., Ryffel B., Oliveira S.C., and Quesniaux VFJ. cGAS/STING pathway is important for dendritic cell activation but is not essential to induce protective immunity against M. tuberculosis infection. J Innate Immun (2018, in press)

  7. Di Padova F, Quesniaux VFJ, Ryffel B. MyD88 as a therapeutic target for inflammatory lung diseases. Expert Opin Ther Targets. 2018 Apr 16. doi: 10.1080/ 14728222.2018.1464139. PMID: 29658361

  8. Cordero MD, Alcocer-Gómez E, Ryffel B. Gain of function mutation and inflammasome driven diseases in human and mouse models. J Autoimmun. 2018 Mar 30. pii: S0896-8411(18)30064-7. doi: 10.1016/j.jaut.2018.03.002. [Epub ahead of print] Review. PMID: 29610014

  9. Anchim A, Raddi N, Zig L, Perrieau P, Le Goffic R, Ryffel B, Benihoud K. Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway. Front Immunol. 2018 Feb 5;9:124. doi: 10.3389/fimmu.2018.00124. eCollection 2018. PMID: 29459860

  10. Palomo J, Quesniaux VFJ, Togbe D, Reverchon F, Ryffel B. Unravelling the Roles of Innate Lymphoid Cells in Cerebral Malaria Pathogenesis. Parasite Immunol 40(2) (2018) doi: 10.1111/pim.12502. [Epub ahead of print] PMID: 29117626 Review

  11. Santos-Durán GN, Ferreiro-Galve S, Menuet A, Mazan S, Rodríguez-Moldes I, Candal E. The Shark Basal Hypothalamus: Molecular Prosomeric Subdivisions and Evolutionary Trends. Front Neuroanat. 2018 Mar 14;12:17. doi: 10.3389/fnana.2018.00017. eCollection 2018. PubMed PMID: 29593505; PubMed Central PMCID: PMC5861214.

  12. Lagadec R, Lanoizelet M, Sánchez-Farías N, Hérard F, Menuet A, Mayeur H, Billoud B, Rodriguez-Moldes I, Candal E, Mazan S. Neurogenetic asymmetries in the catshark developing habenulae: mechanistic and evolutionary implications. Sci
    Rep. 2018 Mar 15;8(1):4616. doi: 10.1038/s41598-018-22851-3. PubMed PMID: 29545638; PubMed Central PMCID: PMC5854604.

  13. Laugeray A, Oummadi A, Jourdain C, Feat J, Meyer-Dilhet G, Menuet A, Plé K, Gay M, Routier S, Mortaud S, Guillemin GJ. Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-L-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in
    Offspring-Potential Involvement of DNA Damage and Oxidative Stress. Neurotox Res. 2018 Jan;33(1):87-112. doi: 10.1007/s12640-017-9802-1. Epub 2017 Sep 6. PubMed PMID: 28879461.

  14. Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I. The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Front Immunol. 2018 Jun 25;9:1476. doi: 10.3389/fimmu.2018.01476. eCollection 2018. PubMed PMID: 29988569; PubMed Central PMCID: PMC6026799.


  15. Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I. Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy. Int J Mol Sci. 2018 Jul 4;19(7). pii: E1959. doi:10.3390/ijms19071959. PubMed PMID: 29973541.

  16. Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VF, Togbé D, Mergny JL, Cook-Moreau J, Cogné M. G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation. J Allergy Clin Immunol. 2018 Jun 20. pii: S0091-6749(18)30895-9. doi: 10.1016/j.jaci.2018.06.011. [Epub ahead of print] PubMed PMID: 29935221.

  17. Benmerzoug S, Marinho FV, Rose S, Mackowiak C, Gosset D, Sedda D, Poisson E, Uyttenhove C, Van Snick J, Jacobs M, Garcia I, Ryffel B, Quesniaux VFJ. GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection. Sci Rep. 2018 Jun 5;8(1):8652. doi: 10.1038/s41598-018-26984-3. PubMed PMID: 29872095; PubMed Central PMCID: PMC5988704.

  18. Dosset M, Vargas TR, Lagrange A, Boidot R, Végran F, Roussey A, Chalmin F, Dondaine L, Paul C, Lauret Marie-Joseph E, Martin F, Ryffel B, Borg C, Adotévi O, Ghiringhelli F, Apetoh L. PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer. Oncoimmunology. 2018 Mar 15;7(6):e1433981. doi:10.1080/2162402X.2018.1433981. eCollection 2018. PubMed PMID: 29872568; PubMed Central PMCID: PMC5980491.

  19. Talbot J, Peres RS, Pinto LG, Oliveira RDR, Lima KA, Donate PB, Silva JR, Ryffel B, Cunha TM, Alves-Filho JC, Liew FY, Louzada-Junior P, de Queiroz Cunha F. Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells. Arthritis Res Ther. 2018 Jun 8;20(1):119. doi: 10.1186/s13075-018-1609-9. PubMed PMID: 29884199; PubMed Central PMCID: PMC5994132.

  20. Saraiva AL, Veras FP, Peres RS, Talbot J, de Lima KA, Luiz JP, Carballido JM, Cunha TM, Cunha FQ, Ryffel B, Alves-Filho JC. Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T(h)17 cells in the lymph nodes. FASEB J. 2018 Jun 12:fj201800285. doi: 10.1096/fj.201800285. [Epub ahead of print] PubMed PMID: 29894669.

  21. Erdei J, Tóth A, Balogh E, Nyakundi BB, Bányai E, Ryffel B, Paragh G, Cordero MD, Jeney V. Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells. Oxid Med Cell Longev. 2018 Mar 20;2018:4310816. doi: 10.1155/2018/4310816. eCollection 2018. PubMed PMID: 29743981; PubMed Central PMCID: PMC5883980.

  22. Martins LMS, Perez MM, Pereira CA, Costa FRC, Dias MS, Tostes RC, Ramos SG, de Zoete MR, Ryffel B, Silva JS, Carlos D. Interleukin-23 promotes intestinal T helper type17 immunity and ameliorates obesity-associated metabolic syndrome in a murine high-fat diet model. Immunology. 2018 May 2. doi: 10.1111/imm.12946. [Epub ahead of print] PubMed PMID: 29722014.



Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I. The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Front Immunol. 2018 Jun 25;9:1476. doi: 10.3389/fimmu.2018.01476. eCollection 2018. PubMed PMID: 29988569; PubMed Central PMCID: PMC6026799.