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Publications

Année 2013 :

1. Atzori, A. ; Baker, A. E. ; Chiu, M. ; Bryce, R. A. ; Bonnet, P.
   Effect of sequence and stereochemistry reversal on p53 peptide mimicry
   PLoS ONE 2013, 8, e68723.
   
   
2. Dubernet, M. ; Duguet, N. ; Colliandre, L. ; Berini, C. ; Helleboid, S. ; Bourotte, M. ; Daillet, M. ; Maingot, L. ; Daix, S. ; Delhomel, J.-F. ; Morin-Allory, L. ; Routier, S. ; Walczak, R.
   Identification of new nonsteroidal RORa ligands; Related structure–activity relationships and docking studies
   ACS Med. Chem. Lett. 2013, 4, 504-508.
   
   
3. Martinez-Sanz, J. ; Bonnet, P. ; Lozano, S. ; Arrault, Al. ; Morin-Allory, L. ; Vayer, P.
   New QSAR models for human cytochromes P450, 1A2, 2D6 and 3A4 implicated in the metabolism of drugs. relevance of dataset on model development
   Molecular Informatics 2013, 32, 573-577.
   
   
4. Mathis, G. ; Bourg, S. ; Aci-Sèche, S. ; Truffert, J.-C. ; Asseline, U.
   Synthesis and Properties of 2’-O-neopentyl modified oligonucleotides
   Organic & Biomolecular Chemistry 2013, 11, 1345-1357.
   
   

Année 2012 :

1. Blanch, N. M. ; Chabot, G. G. ; Quentin, L. ; Scherman, D. ; Bourg, S. ; Dauzonne, D.
   In vitro and in vivo biological evaluation of new 4,5-disubstituted 1,2,3-triazoles as cis-constrained analogues of combretastatin A4
   Eur. J. Med. Chem. 2012, 54, 22-32.
   
   
2. Boulahjar, R. ; Ouach, A. ; Chiurato, M. ; Bourg, S. ; Ravache, M. ; Le Guével, R. ; Marionneau-Lambot, S. ; Oullier, T. ; Lozach, O. ; Meijer, L. ; Guguen-Guillouzo, C. ; Lazar, S. ; Akssira, M. ; Troin, Y. ; Guillaumet, G. ; Routier, S.
   Novel tetrahydropyrido[1,2-a]isoindolone derivatives (Valmerins) : potent cyclin dependant kinase / glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts
   J. Med. Chem. 2012, 55, 9589-9606.
   
   
3. Colliandre, L. ; Le Guilloux, V. ; Bourg, S. ; Morin-Allory, L.
   Visual characterization and diversity quantification of chemical libraries: 2. analysis and selection of size-independent, subspace-specific diversity indices
   J. Chem. Inf. Model. 2012, 52, 327-342.
   
   
4. Grosse, S. ; Pillard, C. ; Massip, S. ; Leger, J. M. ; Jarry, C. ; Bourg, S. ; Bernard, P. ; Guillaumet, G.
   Efficient synthesis and first regioselective C-3 direct arylation of imidazo[1,2-b]pyrazoles
   Chem. Eur. J. 2012, 18, 14943-14947.
   
   
5. Le Guilloux, V. ; Arrault, Al. ; Colliandre, L. ; Bourg, S. ; Vayer, P. ; Morin-Allory, L.
   Mining chemical libraries with "Screening Assistant 2"
   Journal of Cheminformatics 2012, 4, .
   
   
6. Néagoie, C. ; Vedrenne, E. ; Buron, F. ; Mérour, J. Y. ; Rosca, S. ; Bourg, S. ; Lozach, O. ; Meijer, L. ; Baldeyrou, B. ; Lansiaux, A. ; Routier, S.
   Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues : A novel DYRK1A inhibitor class
   Eur. J. Med. Chem. 2012, 49, 379-396.
   
   
7. Ty, N. ; Pontikis, R. ; Chabot, G. G. ; Devillers, E. ; Quentin, L. ; Bourg, S. ; Florent, J.-C.
   Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4
   Bioorg. Med. Chem. 2012, 21, 1357-1366.
   
   

Année 2011 :

1. Arthuis, M. ; Pontikis, R. ; Chabot, G. ; Seguin, J. ; Quentin, L. ; Bourg, S. ; Morin-Allory, L. ; Florent, J.-C.
   Synthesis and structure–activity relationships of constrained heterocyclic analogues of combretastatin A4
   ChemMedChem 2011, 6, 1693-1705.
   
   
2. Kassis, P. ; Brzeszcz, J. ; Bénéteau, V. ; Lozach, O. ; Meyjer, L. ; Le Guével, R. ; Guillouzo, C. ; Lewinski, K. ; Bourg, S. ; Colliandre, L. ; Routier, S. ; Mérour, J. Y.
   Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents
   Eur. J. Med. Chem. 2011, 46, 5416-5434.
   
   
3. Le Guilloux, V. ; Colliandre, L. ; Bourg, S. ; Guenegou, G. ; Dubois-Chevalier, J. ; Morin-Allory, L.
   Visual characterization and diversity quantification of chemical libraries: 1. creation of delimited reference chemical subspaces
   J. Chem. Inf. Model. 2011, 51, 1762-1774.
   
   
4. Novoa,A. ; Pelligrini-Moïse, N. ; Bourg, S. ; Thoret, S. ; Dubois, J. ; Aubert, G. ; Cresteil, T. ; Chapleur, Y.
   Design, synthesis and antiproliferative activities of biarylolefins based on polyhydroxylated and carbohydrate scaffolds
   Eur. J. Med. Chem. 2011, 46, 3570-3580 .
   
   
5. Pin, F. ; Buron, F. ; Saab, F. ; Colliandre, L. ; Bourg, S. ; Schoentgen, F. ; Le Guével, R. ; Guillouzo, C. ; Routier, S.
   Synthesis and biological evaluation of 2,3-bis(het)aryl-4-azaindole derivatives as protein kinase inhibitors
   Med. Chem. Commun. 2011, 2, 899-903.
   
   
6. West, C. ; Guenegou, G. ; Zhang, Y. ; Morin-Allory, L.
   Insights into chiral recognition mechanisms in supercritical fluid chromatography II. Factors contributing to enantiomer separation on tris-(3,5-dimethylphenylcarbamate) amylose and cellulose stationary phases
   J. Chromatogr. A 2011, 1218, 2033-2057.
   
   
7. West, C. ; Zhang, Y. ; Morin-Allory, L.
   Insights into chiral recognition mechanisms in supercritical fluid chromatography I. Non-enantiospecific interactions contributing to the retention on tris-(3,5-dimethylphenylcarbamate) amylose and cellulose stationary phases
   J. Chromatogr. A 2011, 1218, 2019-2032.
   
   

Année 2010 :

1. Blondeau, S. ; Do Q.T. ; Scior, T. ; Bernard, P. ; Morin-Allory, L.
   Reverse pharmacognosy: another way to harness the generosity of nature
   Current Pharmaceutical Design 2010, 16, 1682-1696.
   
   
2. Schmidtke, P. ; Le Guilloux, V. ; Maupetit, J. ; Tuffery, P.
   fpocket: Online tools for protein ensemble pocket detection and tracking
   Nucleic Acids Research 2010, 38, W582-W589.
   
   

Année 2009 :

1. Aci-Sèche, S. ; Garnier, N. ; Genest, D. ; Bourg, S. ; Marot, C. ; Morin-Allory, L. ; Genest, M.
   A Restrained molecular dynamics empirical approach for generating a small set of structures representative of the internal flexibility of a receptor
   QSAR & Combinatorial Science 2009, 28, 959-968.
   
   
2. Le Guilloux, V. ; Schmidtke, P. ; Tuffery, P.
   Fpocket: An open source platform for ligand pocket detection
   BMC Bioinformatics 2009, 10:168, 1-11.
   
   
3. Ty, N. ; Kaffy, J. ; Arrault, Al. ; Thoret, S. ; Pontikis, R. ; Dubois, J. ; Morin-Allory, L. ; Florent, J.
   ynthesis and biological evaluation of cis-locked vinylogous combretastatin-A4 analogues: Derivatives with a cyclopropyl-vinyl or a cyclopropyl-amide bridge
   Bioorg. Med. Chem. Lett. 2009, 19, 1318-1322.
   
   

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